Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can target the ubiquitination and degradation of Smad3, and also improve the HIF-α protein level. It possesses a multi-path anti-fibrosis function and a renal protection function for research of renal anemia. This compound can be utilized for research on prostate cancer and other cancers.
Targets ubiquitination and degradation of Smad3
Improves HIF-α protein level
Possesses multi-path anti-fibrosis function
Provides renal protection function for research of renal anemia
Degrades Smad3 protein in a concentration-dependent manner
Significantly upregulates HIF-2α protein level in rat renal fibroblasts
Can degrade Smad3 protein levels and downregulate the androgen receptor (AR) pathway in CWR22Rv1 cells
Suitable for research on prostate cancer and other cancers
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More